“Egg Industry Response to Choline and TMAO”
Everyone knows that a bad diet can lead to heart disease, but which dietary components are the most harmful? The more of this TMAO stuff people had in their blood, the greater the odds they had heart disease, and the worse their heart disease was. Where does this TMAO stuff come from? Our liver turns TMA into TMAO. OK, where does TMA come from? Certain bacteria in our gut turn something in our diet called choline into TMA. Where is the highest concentration of choline found? Eggs, milk, and meats, including poultry and fish. So when we eat these foods, our gut bacteria may make TMA, which is absorbed into our system and oxidized by our liver into TMAO, which may then increase our risk of heart attack, stroke, and death. How can we be certain that our gut bacteria can take the choline we eat and turn it into trimethylamine in the first place? Just give them some eggs. Have people eat two hard boiled eggs and you get a bump of TMAO in their blood within an hour of consumption. Imagine you work for the American Egg Board, tasked with designing a study to show no effect of eating nearly an egg a day. How could you rig it to show no difference? Well, if you look at the effect of an egg meal, you get a bump in TMAO levels, but your kidneys are so good at getting rid of this nasty stuff, that by hours 4, 6, 8, you’re back to baseline. So all you have to do is just make sure they hadn’t eaten those egg sin the last 12 hours and you can show no effect and get your study published in the Journal of the Academy of Nutrition and Dietetics, and collect your paycheck.
“鸡蛋行业对胆碱和TMAO所采取的对策”
大家都知道不健康的饮食会导致心脏病，但是哪些饮食成分是最有害的呢？（研究发现）人们血液中这种TMAO的含量越多，他们患心脏病的几率就越大，病情也就越严重。
这些TMAO是从哪里来的呢？我们的肝脏将TMA（三甲胺）转化为TMAO。那么TMA又从何而来呢？我们肠道中的某些细菌会将饮食中的胆碱转化为TMA。哪里的胆碱浓度最高呢？鸡蛋，牛奶和肉类，包括家禽和鱼。
所以当我们吃这些食物时，我们的肠道细菌可能会产生TMA，这些TMA被我们的系统吸收并被肝脏氧化成TMAO，这可能会增加我们心脏病发作、中风和死亡的风险。
我们怎么能确定我们的肠道细菌在一开始就能把我们吃的胆碱转化为三甲胺呢（TMA）？只要让人们吃一些鸡蛋就好啦。让他们吃两个煮熟的鸡蛋，你就会发现他们血液中的TMAO在一小时内激增。
想象一下你在为美国鸡蛋委员会工作，你的任务是设计一项研究来证明每天吃近一个鸡蛋对身体不会产生任何影响。那你要怎么操纵这项研究，才能使它对身体没有影响呢？如果你观察一顿含蛋餐食对身体的影响，你会发现你的TMAO值在吃了鸡蛋以后上升了，但你的肾脏却非常擅于清除这些令人讨厌的东西，所以在4、6、8个小时后，你的TMAO值会回到基准值。所以你所要做的就是确保人们在过去的12个小时里没有吃鸡蛋，这样你就能得出TMAO值不会改变的结果了，并且将你的研究发表在《营养与饮食研究期刊》上，然后你就可以拿到薪水啦。 #常观世音微语录#